Three-dimensional structure of iminodisuccinate epimerase defines the fold of the MmgE/PrpD protein family
B Lohkamp, B Bäuerle, PG Rieger… - Journal of molecular …, 2006 - Elsevier
… any protein of known 3D structure … epimerase is a member of the MmgE/PrpD protein family.
As one step in the study of this novel epimerase we have determined the structure by protein …
As one step in the study of this novel epimerase we have determined the structure by protein …
[HTML][HTML] Enzymatic reaction mechanism of cis-aconitate decarboxylase based on the crystal structure of IRG1 from Bacillus subtilis
HL Chun, SY Lee, SH Lee, CS Lee, HH Park - Scientific Reports, 2020 - nature.com
… that for iminodisuccinate (IDS) epimerase, a structural homolog of … exhibits the typical fold of
the MmgE/PrpD family containing two … cis-aconitate is docked into this defined grid box of the …
the MmgE/PrpD family containing two … cis-aconitate is docked into this defined grid box of the …
[HTML][HTML] In-silico characterization and structure-based functional annotation of a hypothetical protein from Campylobacter jejuni involved in propionate catabolism
… the HP with other MmgE/PrpD family protein and cis-aconitate … and a smaller domain that
folds into an alpha + beta domain [… proteins with an unknown three-dimensional structure, and …
folds into an alpha + beta domain [… proteins with an unknown three-dimensional structure, and …
Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production
A Michelucci, T Cordes, J Ghelfi… - Proceedings of the …, 2013 - National Acad Sciences
… the MmgE/PrpD family (17), which contains some proteins for … Each bar represents the
average expression fold change (± … gene and are shown as average expression fold change (± …
average expression fold change (± … gene and are shown as average expression fold change (± …
[HTML][HTML] Characterization and engineering of branched short-chain dicarboxylate metabolism in Pseudomonas reveals resistance to fungal 2-hydroxyparaconate
… A unique function within the MmgE/PrpD family was revealed for an iminodisuccinate (IDS) …
MmgE/PrpD family protein shared the highest structure identity with the IDS epimerase from A…
MmgE/PrpD family protein shared the highest structure identity with the IDS epimerase from A…
Itaconic acid production by filamentous fungi in starch-rich industrial residues
R Bafana, S Sivanesan, RA Pandey - Indian Journal of Microbiology, 2017 - Springer
… iminodisuccinate epimerase and 2-methylcitrate dehydratase enzymes, both of which belong
to MmgE/PrpD family of proteins… As C1 and C2 showed around 1000 fold higher production …
to MmgE/PrpD family of proteins… As C1 and C2 showed around 1000 fold higher production …
A clone-based transcriptomics approach for the identification of genes relevant for itaconic acid production in Aspergillus
A Li, N van Luijk, M ter Beek, M Caspers, P Punt… - Fungal genetics and …, 2011 - Elsevier
… In this approach, the fold difference in expression between the … In our analysis, the fold
difference in expression level was … on functional characterization of the MmgE/PrpD family gene. …
difference in expression level was … on functional characterization of the MmgE/PrpD family gene. …
Crystal structure of cis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis
F Chen, P Lukat, AA Iqbal, K Saile… - Proceedings of the …, 2019 - National Acad Sciences
… structure of hCAD (comprising residues 4 to 461) was determined by molecular replacement
with the structure of iminodisuccinate epimerase (… the same fold as the mammalian proteins, …
with the structure of iminodisuccinate epimerase (… the same fold as the mammalian proteins, …
RmlC, a C3′ and C5′ carbohydrate epimerase, appears to operate via an intermediate with an unusual twist boat conformation
C Dong, LL Major, V Srikannathasan, JC Errey… - Journal of molecular …, 2007 - Elsevier
… Here we report the structure of RmlC from several organisms … NovW, a validated C3′
mono-epimerase involved in … the enzyme iminodisuccinate epimerase, which has a novel fold, has …
mono-epimerase involved in … the enzyme iminodisuccinate epimerase, which has a novel fold, has …
[HTML][HTML] The crystal structure of mouse IRG1 suggests that cis-aconitate decarboxylase has an open and closed conformation
HL Chun, SY Lee, KH Kim, CS Lee, TJ Oh, HH Park - Plos one, 2020 - journals.plos.org
… The structure was determined using the molecular replacement (MR) phasing method with
PHASER [24]. The previously solved structural homologue iminodisuccinate (IDS) epimerase …
PHASER [24]. The previously solved structural homologue iminodisuccinate (IDS) epimerase …